Benefits of Collisional Cross Section Assisted Precursor Selection (caps-PASEF) for Cross-linking Mass Spectrometry.

bioRxiv. Apr 18 2020

Steigenberger B, van den Toorn VP, Bijl E, Greisch JF, Raether O, Lubeck M, Pieters RJ, Heck AJR, Scheltema RA

Simplified high-throughput methods for deep proteome analysis on the timsTOF Pro.

bioRxiv. 2019 Jun 3. 

JJ Sandow, Infusini G, Dagley LF, Larsen RH, Webb AI 

 

A regulatory interface on RIPK2 is required for XIAP binding and NOD signaling activity.

bioRxiv. 2020 Mar 12.

VJ Heim, Dagley LF, Stafford CA, Hansen FM, Clayer E, Bankovacki A, Webb AI, Lucet IS, Silke J, Nachbur U.

 

CryoEM structure of the Vibrio cholerae Type IV competence pilus secretin PilQ.

bioRxiv. 2020 Mar 4.

Weaver SJ, Sazinsky MH, Dalia TN, Dalia AB, Jensen GJ

Single-cell mass-spectrometry quantifies the emergence of macrophage heterogeneity.

bioRxiv. 2019 Dec 5.

Specht H, Emmott E, Petelski AA, Huffman RG, Perlman DH, Serra M, Kharchenko P, Koller A, Slavov N.

MS Imaging-guided Microproteomics for Spatial Omics on a Single Instrument.

Proteomics.  2020 Aug 7.

Dewez F, Oejten J, Henkel C, Hebeler R, Neuweger H, Pauw ED, Heeren RMA, Balluff B

A standardized, innovative method to characterize the structure of aquatic protein hydrolysates.

Heliyon 2020 Jun 13;6(6)

Leduc A, Fournier V, Henry J

Identification of novel interacting partners of the NEDD4 ubiquitin ligase in mouse testis.

J Proteomics 2020 May 22;223:103830.

Manning JA, Windley SP, Sandow JJ, Shah SS, Western P, Wilhelm D, Kumar S

Exploration of human cerebrospinal fluid: A large proteome dataset revealed by trapped ion mobility time-of-flight mass spectrometry.

Data Brief 2020 May 16;31:105704.

Macron C, Lavigne R, Galindo AN, Affolter M, Pineau C, Dayon L

 

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC.

Nat Cell Biol 2020 Jun;22(6):663-673.

Fuseya Y, Fujita H, Kim M, Ohtake F, Nishide A, Sasaki K, Saeki Y, Tanaka K, Takahashi R, Iwai K

-Omic analysis of Sepia officinalis white body: new insights into multifunctionality and haematopoiesis regulation.

J Proteome Res. Benoist L, Corre E, Bernay B, Henry J, Zatylny-Gaudin C

 

Investigation of caprine milk serum proteome and glycated proteome changes during heat treatment using robust ion mobility time-of-flight proteomic techniques.

International Dairy Journal. Roy MC, Zhang L, Liu X, Zhou P

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response.

Front Immunol. 2020 May 12;11:887.  

James G Bedford, Giuseppe Infusini, Laura F Dagley, Fernando Villalon-Letelier, Ming Z M Zheng, Vicki Bennett-Wood, Patrick C Reading, Linda M Wakim

O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins.

Front Chem. 2020 Apr 28;8:318.

Narek Darabedian, Bo Yang, Richie Ding, Giuliano Cutolo, Balyn W Zaro, Christina M Woo, Matthew R Pratt

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity.

Science Advances. 2020 Apr 29;6(18):eaaz5041.

Fan Z, Devlin JR, Hogg SJ, Doyle MA, Harrison PF, Todorovski I, Cluse LA, Knight DA, Sandow JJ, Gregory G, Fox A, Beilharz TH, Kwiatkowski N, Scott NE, Vidakovic AT, Kelly GP, Svejstrup JQ, Geyer M, Gray NS, Vervoort SJ, Johnstone RW. 

 

UBR E3 Ligases and the PDIA3 Protease Control Degradation of Unfolded Antibody Heavy Chain by ERAD.

J Cell Biol. 2020 Jul 6;219(7):e201908087.

Danming Tang, Wendy Sandoval, Cynthia Lam, Benjamin Haley, Peter Liu, Di Xue, Deepankar Roy, Tom Patapoff, Salina Louie, Brad Snedecor, Shahram Misaghi

 

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor.

Structure. 2020 May 26:S0969-2126(20)30171-4.

Xu Y, Kirk NS, Venugopal H, Margetts MB, Croll TI, Sandow JJ, Webb AI, Delaine CA, Forbes BE, Lawrence MC. 

 

Dephosphorylation of cGAS by PPP6C Impairs Its Substrate Binding Activity and Innate Antiviral Response.

Protein Cell. 2020 May 30. https://doi.org/10.1007/s13238-020-00729-3.

Mi Li, Hong-Bing Shu

 

ROCK-mediated selective activation of PERK signalling causes fibroblast reprogramming and tumour progression through a CRELD2-dependent mechanism.

Nat Cell Biol. 2020 May 25. https://doi.org/10.1038/s41556-020-0523-y.

Boyle ST, Poltavets V, Kular J, Pyne NT, Sandow JJ, Lewis AC, Murphy KJ, Kolesnikoff N, Moretti PAB, Tea MN, Tergaonkar V, Timpson P, Pitson SM, Webb AI, Whitfield RJ, Lopez AF, Kochetkova M, Samuel MS

Quantitative Proteomics Reveals Docosahexaenoic Acid-Mediated Neuroprotective Effects in Lipopolysaccharide-Stimulated.

Microglial Cells. J Proteome Res. 2020 Apr 27. doi: https://doi.org/10.1021/acs.jproteome.9b00792.

Yang B, Li R, Liu PN, Geng X, Mooney BP, Chen C, Cheng J, Fritsche KL, Beversdorf DQ, Lee JC, Sun GY, Greenlief CM

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.

Commun Biol. 2020 Apr 3;3(1):163. doi: https://doi.org/10.1038/s42003-020-0882-8.

Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F

RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.

Nat Struct Mol Biol. 2020 Apr;27(4):323-332. 

Matsuo Y, Tesina P, Nakajima S, Mizuno M, Endo A, Buschauer R, Cheng J, Shounai O, Ikeuchi K, Saeki Y, Becker T, Beckmann R, Inada T


Structure and Function of an Elongation Factor P Subfamily in Actinobacteria.

Cell Reports. 2020 Mar 31;30(13):4332-4342.e5.

Pinheiro B, Scheidler CM, Kielkowski P, Schmid M, Forné I, Ye S, Reiling N, Takano E, Imhof A, Sieber SA, Schneider S, Jung K

MaxQuant software for ion mobility enhanced shotgun proteomics.

Molecular and Cellular Proteomics. 2020 Mar 10.

Prianichnikov N, Koch H, Koch S, Lubeck M, Heilig R, Brehmer S, Fischer R, Cox J.

 

Proteogenomic analysis of granulocyte macrophage colony- stimulating factor autoantibodies in the blood of a patient with autoimmune pulmonary alveolar proteinosis.

Scientific Reports. 2020 Mar 18;10(1):4923.

Hashimoto A, Takeuchi S, Kajita R, Yamagata A, Kakui R, Tanaka T, Nakata K.

 

Structure of the neurotensin receptor 1 in complex with β-arrestin 1.

Nature. 2020 Mar;579(7798):303-308.

Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK.

 

PIKES Analysis Reveals Response to Degraders and Key Regulatory Mechanisms of the CRL4 Network.

Molecular Cell. 2020 Mar 5;77(5):1092-1106.e9.

Reichermeier KM, Straube R, Reitsma JM, Sweredoski MJ, Rose CM, Moradian A, den Besten W, Hinkle T, Verschueren E, Petzold G, Thomä NH, Wertz IE, Deshaies RJ, Kirkpatrick DS.

 

NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS.

Journal of Experimental Medicine. 2020 May 4;217(5).

Louis C, Guimaraes F, Yang Y, D'Silva D, Kratina T, Dagley L, Hediyeh-Zadeh S, Rautela J, Masters SL, Davis MJ, Babon JJ, Ciric B, Vivier E, Alexander WS, Huntington ND, Wicks IP.

 

A proteomic study of resistance to Brown Ring disease in the Manila clam, Ruditapes philippinarum.

Fish and Shellfish Immunology. 2020 Apr;99:641-653.

Smits M, Artigaud S, Bernay B, Pichereau V, Bargelloni L, Paillard C.

 

Dynamic Regulation of Mitochondrial Import by the Ubiquitin System.

Molecular Cell. 2020 Mar 5;77(5):1107-1123.e10.

Phu L, Rose CM, Tea JS, Wall CE, Verschueren E, Cheung TK, Kirkpatrick DS, Bingol B.

Identification of 56 Proteins Involved in Embryo-Maternal Interactions in the Bovine Oviduct.

International Journal of Molecular Sciences. 2020 Jan 11;21(2).

Banliat C, Tsikis G, Labas V, Teixeira-Gomes AP, Com E, Lavigne R, Pineau C, Guyonnet B, Mermillod P, Saint-Dizier M.

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis.

Nature Chemical Biology. 2019 Nov;15(11):1057-1066.

van Delft MF, Chappaz S, Khakham Y, Bui CT, Debrincat MA, Lowes KN, Brouwer JM, Grohmann C, Sharp PP, Dagley LF, Li L, McArthur K, Luo MX, Chin HS, Fairlie WD, Lee EF, Segal D, Duflocq S, Lessene R, Bernard S, Peilleron L, Nguyen T, Miles C, Wan SS, Lane RM, Wardak A, Lackovic K, Colman PM, Sandow JJ, Webb AI, Czabotar PE, Dewson G, Watson KG, Huang DCS, Lessene G, Kile BT.

Regulation of macrophage activity by surface receptors contained within Borrelia burgdorferi-enriched phagosomal fractions.

PLoS Pathology. 2019 Nov 18;15(11):e1008163.

Carreras-González A, Barriales D, Palacios A, Montesinos-Robledo M, Navasa N, Azkargorta M, Peña-Cearra A, Tomás-Cortázar J, Escobes I, Pascual-Itoiz MA, Hradiská J, Kopecký J, Gil-Carton D, Prados-Rosales R, Abecia L, Atondo E, Martín I, Pellón A, Elortza F, Rodríguez H, Anguita J.

RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses.

Immunology and Cell Biology. 2019 Oct;97(9):840-852.

Hayman TJ, Hsu AC, Kolesnik TB, Dagley LF, Willemsen J, Tate MD, Baker PJ, Kershaw NJ, Kedzierski L, Webb AI, Wark PA, Kedzierska K, Masters SL, Belz GT, Binder M, Hansbro PM, Nicola NA, Nicholson SE.

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.

Cell Reports. 2019 Sep 24;28(13):3309-3319.e5.

Petrie EJ, Sandow JJ, Lehmann WIL, Liang LY, Coursier D, Young SN, Kersten WJA, Fitzgibbon C, Samson AL, Jacobsen AV, Lowes KN, Au AE, Jousset Sabroux H, Lalaoui N, Webb AI, Lessene G, Manning G, Lucet IS, Murphy JM.

STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes.

EMBO Reports. 2019 Nov 5;20(11):e48150.

Martin AP, Jacquemyn M, Lipecka J, Chhuon C, Aushev VN, Meunier B, Singh MK, Carpi N, Piel M, Codogno P, Hergovich A, Parrini MC, Zalcman G, Guerrera IC, Daelemans D, Camonis JH.

The MPK8-TCP14 pathway promotes seed germination in Arabidopsis.

The Plant Journal. 2019 Nov;100(4):677-692.

Zhang W, Cochet F, Ponnaiah M, Lebreton S, Matheron L, Pionneau C, Boudsocq M, Resentini F, Huguet S, Blázquez MÁ, Bailly C, Puyaubert J, Baudouin E.

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity.

Science Signaling. 2019 Aug 27;12(596).

Rautela J, Dagley LF, de Oliveira CC, Schuster IS, Hediyeh-Zadeh S, Delconte RB, Cursons J, Hennessy R, Hutchinson DS, Harrison C, Kita B, Vivier E, Webb AI, Degli-Esposti MA, Davis MJ, Huntington ND, Souza-Fonseca-Guimaraes F.

Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics.

Journal of Proteome Research. 2019 Jul 5;18(7):2915-2924.

Dagley LF, Infusini G, Larsen RH, Sandow JJ, Webb AI.

 

Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma.

Nature Communications. 2019 Mar 29;10(1):1421. 

Bachmaier S, Volpato Santos Y, Kramer S, Githure GB, Klöckner T, Pepperl J, Baums C, Schenk R, Schwede F, Genieser HG, Dupuy JW, Forné I, Imhof A, Basquin J, Lorentzen E, Boshart M.

Importance of Pyruvate Sensing and Transport for the Resuscitation of Viable but Nonculturable Escherichia coli K-12.

Journal of Bacteriology. 2019 Jan 11;201(3).

Vilhena C, Kaganovitch E, Grünberger A, Motz M, Forné I, Kohlheyer D, Jung K.

VDAC2 enables BAX to mediate apoptosis and limit tumor development.

Nature Communications. 2018 Nov 26;9(1):4976. 

Chin HS, Li MX, Tan IKL, Ninnis RL, Reljic B, Scicluna K, Dagley LF, Sandow JJ, Kelly GL, Samson AL, Chappaz S, Khaw SL, Chang C, Morokoff A, Brinkmann K, Webb A, Hockings C, Hall CM, Kueh AJ, Ryan MT, Kluck RM, Bouillet P, Herold MJ, Gray DHD, Huang DCS, van Delft MF, Dewson G.

 

High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform.

Nature Protocols. 2018 Sep;13(9):1897-1916. 

Humphrey SJ, Karayel O, James DE, Mann M.

 

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.

Nature Communications. 2018 Jun 21;9(1):2422.

Petrie EJ, Sandow JJ, Jacobsen AV, Smith BJ, Griffin MDW, Lucet IS, Dai W, Young SN, Tanzer MC, Wardak A, Liang LY, Cowan AD, Hildebrand JM, Kersten WJA, Lessene G, Silke J, Czabotar PE, Webb AI, Murphy JM.

Copyright 2020. Patents Pending. All Rights Reserved.  

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